B-hSERPINE2 mice
| Strain Name | C57BL/6-Serpine2tm1(SERPINE2)Bcgen/Bcgen | Common Name | B-hSERPINE2 mice |
| Background | C57BL/6 | Catalog number |
111271 |
|
Aliases |
GDN, GDNPF, PI-7, PI7, PN-1, PN1, PNI | ||
模型验证
mRNA expression analysis
Protein expression analysis
Strain specific analysis of SERPINE2 gene expression in wild-type mice and B-hSERPINE2 mice by RT-PCR. Mouse SERPINE2 mRNA was detectable in lung of wild-type mice (+/+). Human SERPINE2 mRNA was detectable only in lung of homozygous B-hSERPINE2 but not in wild-type mice.
Western blot analysis of SERPINE2 protein expression in homozygous B-hSERPINE2 mice. Various tissue lysates were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hSERPINE2 mice (H/H), and then analyzed by western blot with species-specific anti-SERPINE2 antibody. 40 μg total proteins were loaded for western blotting analysis. SERPINE2 was detected in brain, spleen, lung, and ovary.
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