B-hMUC17 mice
| Strain Name | C57BL/6N-Muc3tm1(MUC17)Bcgen/Bcgen | Common Name | B-hMUC17 mice |
| Background | C57BL/6N | Catalog number | 111292 |
|
Aliases |
MUC17, MUC-17, MUC-3, MUC3, mucin 17, cell surface associated | ||
模型验证
mRNA expression analysis
Protein expression analysis
Strain specific analysis of MUC17 gene expression in wild type (WT) mice and B-hMUC17 mice by RT-PCR. Mouse Muc3 mRNA was detectable only in small intestines of WT mice (+/+). Human MUC17 mRNA was detectable only in homozygous B-hMUC17 mice (H/H) but not in WT mice (+/+).
Strain specific MUC17 expression analysis in homozygous B-hMUC17 mice by flow cytometry. Single-cell suspension obtained from intestinal tissue homogenates of wild type (WT) mice (+/+) and homozygous B-hMUC17 mice (H/H), and analyzed by flow cytometry with anti-human MUC17 antibody. Human MUC17 was exclusively detectable in homozygous B-hMUC17 mice (H/H) but not in WT mice (+/+).
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