Strain Name |
C57BL/6-Epcamtm1(EPCAM)Bcgen/Bcgen |
Common Name | B-hEPCAM mice |
Background | C57BL/6 | Catalog number | 110826 |
Aliases |
EPCAM (Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1) |
Strain specific EPCAM expression analysis in homozygous B-hEPCAM mice by flow cytometry. Lung, small intestine and pancreas were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hEPCAM mice (H/H), and CD45- cells were analyzed by flow cytometry with species-specific anti-EPCAM antibody. Mouse EPCAM was detectable in wild-type mice. Human EPCAM was exclusively detectable in homozygous B-hEPCAM (H/H) but not in wild-type mice.
EpCAM-targeting CAR-T cell immunotherapy is safe and efficacious for epithelial tumors.pdf
When using the B-hEPCAM mouse strain in a publication, please indicate the originate from Biocytogen and stock #110826 in your Materials and Methods section.