B-hDLL3 mice
| Strain Name | C57BL/6N-Dll3tm1(DLL3)Bcgen/Bcgen | Common Name | B-hDLL3 mice |
| Background | C57BL/6N | Catalog number | 110926 |
| Aliases |
DLL3, SCDO1, delta like canonical Notch ligand 3 |
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模型验证
mRNA expression analysis
Protein expression analysis
Strain specific analysis of DLL3 gene expression in wild type (WT) mice and B-hDLL3 mice by RT-PCR. Mouse Dll3 mRNA was detectable in testis of WT mice (+/+). Human DLL3 mRNA was detectable in homozygous B-hDLL3 mice (H/H) but not in WT mice (+/+).
Strain specific DLL3 expression analysis in homozygous B-hDLL3 mice by western blot. Testis and lung were collected from wild type (WT) mice (+/+) and homozygous B-hDLL3 mice (H/H), and analyzed by western blot with anti-DLL3 antibody. DLL3 was detectable in WT mice (+/+) and homozygous B-hDLL3 mice (H/H) due to the cross-reactivity of antibodies.
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