B-hCD80 mice
| Strain Name |
C57BL/6-Cd80tm1(CD80)Bcgen/Bcgen |
Common Name | B-hCD80 mice |
| Background | C57BL/6 | Catalog number | 110935 |
|
Related Genes |
B7、BB1、B7-1、B7.1、LAB7、CD28LG、CD28LG1 | ||
模型验证
mRNA expression analysis
Strain specific analysis of CD80 gene expression in wild type (WT) mice and B-hCD80 mice by RT-PCR. Mouse Cd80 mRNA was detectable only in splenocytes of WT mice (+/+). Human CD80 mRNA was detectable only in homozygous B-hCD80 mice (H/H) but not in WT mice (+/+).
Strain specific CD80 expression analysis in homozygous B-hCD80 mice by flow cytometry. Peritoneal exudative macrophages (PEMs) were collected from wild type (WT) mice (+/+) and homozygous B-hCD80 mice (H/H), and analyzed by flow cytometry with species-specific anti-CD80 antibody. Mouse CD80 was detectable in WT mice (+/+). Human CD80 was exclusively detectable in homozygous B-hCD80 mice (H/H) but not in WT mice (+/+).
Strain specific CD80 expression analysis in homozygous B-hCD80 mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD80 mice (H/H), and analyzed by flow cytometry with species-specific anti-CD80 antibody. Mouse CD80 was detectable in WT mice (+/+). Human CD80 was exclusively detectable in homozygous B-hCD80 mice (H/H) but not in WT mice (+/+).
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