B-hCD3E/hCD38 mice
| Strain Name |
C57BL/6-Cd3etm2(CD3E)Bcgen Cd38tm3(CD38)Bcgen/Bcgen
|
Common Name | B-hCD3E/hCD38 mice |
| Background | C57BL/6 | Catalog number | 111873 |
|
Related Genes |
CD3E, IMD18, T3E, TCRE, CD3e molecule; CD38, ADPRC 1, ADPRC1, CD38 molecule | ||
模型验证
Protein expression analysis in T cells
Strain specific CD3E expression analysis in homozygous B-hCD3E/hCD38 mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD3E/hCD38 mice (H/H;H/H), and analyzed by flow cytometry with species-specific anti-CD3ε antibody. Mouse CD3E was detectable in WT mice (+/+). Human CD3E was exclusively detectable in homozygous B-hCD3E/hCD38 mice (H/H;H/H) but not in WT mice (+/+).
Strain specific CD38 expression analysis in homozygous B-hCD3E/hCD38 mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD3E/hCD38 mice (H/H;H/H), and analyzed by flow cytometry with species-specific anti-CD38 antibody. Mouse CD38 was detectable in WT mice (+/+). Human CD38 was exclusively detectable in homozygous B-hCD3E/hCD38 mice (H/H;H/H) but not in WT mice (+/+).
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