B-hIL17RB mice
| Strain Name | C57BL/6-Il17rbtm1(IL17RB)/Bcgen | Common Name | B-hIL17RB mice |
| Background | C57BL/6 | Catalog number | 110090 |
|
Related Genes |
IL17RB, interleukin 17 receptor B, CRL4, EVI27, IL17BR, IL17RH1 | ||
|
NCBI Gene ID |
50905 | ||
模型验证
mRNA expression analysis
Strain specific analysis of IL17RB gene expression in wild type (WT) mice and B-hIL17RB mice by RT-PCR.
Mouse Il17rb mRNA was detectable only in thymus of WT mice (+/+). Human IL17RB mRNA was detectable only in homozygous B-hIL17RB mice (H/H) but not in WT mice (+/+).
Protein expression analysis-Macrophages
Strain specific IL17RB expression analysis in homozygous B-hIL17RB mice by flow cytometry.
Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hIL17RB mice (H/H), and analyzed by flow cytometry with species-specific anti-IL17RB antibody. Mouse IL17RB was detectable in WT mice (+/+) mice due to the cross-reactivity of antibodies. Human IL17RB was detectable in homozygous B-hIL17RB mice (H/H).
Strain specific IL17RB expression analysis in homozygous B-hIL17RB mice by flow cytometry.
Hepatocytes were collected from wild type (WT) mice (+/+) and homozygous B-hIL17RB mice (H/H), and analyzed by flow cytometry with species-specific anti-IL17RB antibody. Mouse IL17RB was detectable in WT mice (+/+) mice due to the cross-reactivity of antibodies. Human IL17RB was detectable in homozygous B-hIL17RB mice (H/H).
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