Strain Name |
C57BL/6N-Gprc5dtm1(GPRC5D)Bcgen/Bcgen
|
Common Name | B-hGPRC5D mice |
Background | C57BL/6N | Catalog number | 111240 |
Related Genes |
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mRNA expression analysis
Strain specific analysis of GPRC5D gene expression in wild-type C57BL/6 mice and B-hGPRC5D mice by RT-PCR. Mouse Gprc5d mRNA was detectable only in testis of wild-type C57BL/6 mice (+/+). Human GPRC5D mRNA was detectable only in homozygous B-hGPRC5D mice (H/H), but not in wild-type mice.
Protein expression analysis
【1】 Smith E L , Harrington K , Staehr M , et al. CAR T Cell Therapy Targeting G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D), a Novel Target for the Immunotherapy of Multiple Myeloma[J]. Blood, 2018, 132(Supplement 1):589-589.