Strain specific CD200R expression analysis in heterozygous B-hCD200R mice by flow cytometry.
Peritoneal exudative macrophages were collected from wild type (WT) mice (+/+) and heterozygous B-hCD200R mice (H/+), and analyzed by flow cytometry with species-specific anti-CD200R antibody. Mouse CD200R was detectable in WT mice (+/+) and heterozygous B-hCD200R mice (H/+). Human CD200R was exclusively detectable in heterozygous B-hCD200R mice (H/+) but not in WT mice (+/+).
发表文章
【1】Rygiel T P, Luijk B, Meyaard L. Use of an anti-CD200 antibody for prolonging the survival of allografts: a patent evaluation of WO2012106634A1[J]. Expert opinion on therapeutic patents, 2013, 23(3): 389-392.