Strain Name | C57BL/6-Cd3etm2(hCD3E)Bcgen Egfrtm2(EGFR)Bcgen/Bcgen | Common Name | B-hCD3E/hEGFR mice |
Background | C57BL/6 | Catalog number | 121250 |
Related Genes |
ERBB, ERBB1, HER1, NISBD2, PIG61, mENA; IMD18, T3E, TCRE |
Strain specific analysis of EGFR gene expression in wild type (WT) mice and B-hCD3E/hEGFR mice by RT-PCR. Mouse Egfr mRNA was detectable only in liver, lung and kidney of WT mice (+/+). Human EGFR mRNA was detectable only in homozygous B-hCD3E/hEGFR mice (H/H; H/H) but not in WT mice (+/+). The positive band was confirmed to be correct by sequencing.