| Strain Name |
C57BL/6N-Cxcr6tm1(CXCR6)Bcgen/Bcgen
|
Common Name | B-hCXCR6 mice |
| Background | C57BL/6N | Catalog number |
111186 |
|
Related Genes |
CXCR6 (BONZO, CD186, STRL33, TYMSTR) | ||
Protein expression analysis-splenocytes
Strain specific CXCR6 expression analysis in homozygous B-hCXCR6 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hCXCR6 mice (H/H). Protein expression was analyzed with anti-mouse CXCR6 antibody (Biolegend, 151105) and anti-human CXCR6 antibody (Biolegend, 356003) by flow cytometry. mCXCR6 was detectable in T cells, NK cells, and NKT cells of splenocytes in wild-type mice, hCXCR6 was detectable in T cells, NK cells, and NKT cells of splenocytes in homozygous B-hCXCR6 mice.
Strain specific CXCR6 expression analysis in homozygous B-hCXCR6 mice by flow cytometry. Liver was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hCXCR6 mice (H/H). Protein expression was analyzed with anti-mouse CXCR6 antibody (Biolegend, 151105) and anti-human CXCR6 antibody (Biolegend, 356003) by flow cytometry. mCXCR6 was detectable in T cells and NK cells of liver in wild-type mice, hCXCR6 was detectable in T cells and NK cells of liver in homozygous B-hCXCR6 mice.
Strain specific CXCR6 expression analysis in homozygous B-hCXCR6 mice by flow cytometry. Liver was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hCXCR6 mice (H/H). Protein expression was analyzed with anti-mouse CXCR6 antibody (Biolegend, 151105) and anti-human CXCR6 antibody (Biolegend, 356003) by flow cytometry. mCXCR6 was detectable in DCs and monocytes of liver in wild-type mice, hCXCR6 was detectable in DCs and monocytes of liver in homozygous B-hCXCR6 mice.
Strain specific CXCR6 expression analysis in homozygous B-hCXCR6 mice by flow cytometry. Lung was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hCXCR6 mice (H/H). Protein expression was analyzed with anti-mouse CXCR6 antibody (Biolegend, 151105) and anti-human CXCR6 antibody (Biolegend, 356003) by flow cytometry. mCXCR6 was detectable in T cells of lung in wild-type mice, hCXCR6 was detectable in T cells of lung in homozygous B-hCXCR6 mice.
Protein expression analysis-spleen
A: Human CXCL16 could bind to mouse CXCR6 in NK cells of wild-type C57BL/6 mice, but mouse CXCL16 could not bind to human CXCR6 in NK cells of B-hCXCR6 mice (111186).
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